Drug Development

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Listings
  • 5-Bromoindole

    5-Bromoindole

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    5-Bromoindole is a GSK-3 inhibitor. https://www.bocsci.com/5-bromoindole-cas-10075-50-0-item-158606.html

  • FM19G11

    FM19G11

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    FM19G11 is a hypoxia inducible factors α (HIFα) inhibitor. It has been reported to inhibit transcriptional activity of pluripotency markers (Sox2 and Oct4) in rodent and human stem cells under hypoxic conditions. https://www.bocsci.com/fm19g11-cas-32...

  • D-3

    D-3

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    D-3 is a peptide exhibits toxicity in cultured iPSCs and ESCs after 1h of incubation. https://www.bocsci.com/d-3-cas-1967815-98-0-item-286100.html

  • Phenanthroline

    Phenanthroline

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    Phenanthroline was shown to promote differentiation of hPSC into cranial placode cells. https://www.bocsci.com/phenanthroline-cas-66-71-7-item-346824.html

  • Crotonic acid

    Crotonic acid

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    Crotonic acid can induce histone modifications in chemically induced pluripotent stem cells (CiPSCs). https://www.bocsci.com/crotonic-acid-cas-107-93-7-item-13778.html

  • ML 184

    ML 184

    Drug Development Shirley (New York) February 13, 2020 Check with publisher

    ML 184 is a potent agonist of GPR55 (EC50 = 250 nM). Study demonstrated that ML 184 induced proliferation and differentiation of neural stem cells (NSC). https://www.bocsci.com/ml-184-cas-794572-10-4-item-286099.html

  • Surfen dihydrochloride

    Surfen dihydrochloride

    Drug Development Shirley (New York) February 12, 2020 Check with publisher

    Surfen dihydrochloride is a heparin sulfate antagonist that binds to heparins and glycosaminoglycans. Surfen neutralized the anticoagulant activity of both unfractionated and low molecular weight heparins and inhibited enzymatic sulfation and degrada...

  • Pinacidil monohydrate

    Pinacidil monohydrate

    Drug Development Shirley (New York) February 12, 2020 Check with publisher

    Pinacidil monohydrate is a potassium channel activator, and used as an antihypertensive. https://www.bocsci.com/pinacidil-monohydrate-cas-85371-64-8-item-381074.html

  • Epiblastin A

    Epiblastin A

    Drug Development Shirley (New York) February 12, 2020 Check with publisher

    Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. It converts epiblast stem cells (EpiSC) into embryonic stem cells (ESC) and enhances ESC self-renewal. https://www.bocsci.com/epiblastin-a-cas-16470-02-3-item-286096.html

  • N-hydroxy-2-oxo-3-(3-phenylpropyl)-1,2-dihydroquinoxaline-6-carboxamide

    N-hydroxy-2-oxo-3-(3-phenylpropyl)-1,2-dihydroquinoxaline-6-carboxamide

    Drug Development Shirley (New York) February 12, 2020 Check with publisher

    N-hydroxy-2-oxo-3-(3-phenylpropyl)-1,2-dihydroquinoxaline-6-carboxamide is a quinoxaline compound that can induce neuronal differentiation in PC12 and rat MSC (mesenchymal stem cell) cultures. https://www.bocsci.com/n-hydroxy-2-oxo-3-3-phenylpropyl-1...

  • Isoxazole

    Isoxazole

    Drug Development Shirley (New York) February 12, 2020 Check with publisher

    Isoxazole can act as an acetylcholinesterase (AChE) inhibitor. https://www.bocsci.com/isoxazole-cas-288-14-2-item-11240.html

  • 1-Oleoyl lysophosphatidic acid sodium salt

    1-Oleoyl lysophosphatidic acid sodium salt

    Drug Development Shirley (New York) February 11, 2020 Check with publisher

    1-Oleoyl lysophosphatidic acid sodium salt is an agonist of LPA1 and LPA2 receptors. It was shown to inhibit differentiation of neural stem cells (NSCs) into neurons. https://www.bocsci.com/1-oleoyl-lysophosphatidic-acid-sodium-salt-cas-22556-62-3-it...