Drug Development

Listings

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  Solid Form Screening

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  It is widely accepted that majority of drug candidate compounds are solid in nature and can exist in a broad range of forms, which lead to diverse physicochemical properties, such as particle size, salt from, and others, and even the pharmacological ...

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  Permeability/Partition Coefficient

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Recognizing the fact that less than 10 % of those drug candidates that enter clinical development receive the market access. Majority of drug failures are mainly ascribed to the unfavorable pharmacokinetic, ADME properties, toxicity and adverse side ...

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  Hygroscopicity Testing

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Hygroscopicity of a material can be regarded as a physicochemical property that represents the ability of absorbing moisture from the surrounding environment. Recently, determination of the hygroscopicity is of great importance to select the most app...

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  Polymorph Screening

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Given the fact that the majority of drug substances are produced by crystallization, a single chemical entity generally can adopt two or more crystalline phases, and such phenomenon can be termed as the polymorphism. Although the morphology, solvates...

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  Solubilization Improvement

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Solubility is supposed to be one of the most pivotal parameters for achieving anticipated pharmacological response which requires sufficient concentration of drug in systemic circulation. Given the unpleasant fact that the majority of drug candidates...

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  Preformulation Screening

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Pre-preparation studies were initiated prior to the commencement of pharmaceutical preparation activities. In the pre-preparation stage, the physical and chemical properties of the active drug component (API) were determined. For chemical API, the kn...

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  Formulation Services

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  As a fundamental part of the pharmaceutical product development, an appropriate formulation development contributes to the optimal drug delivery performance, stability, and pharmacokinetics (PK), potency. With clear awareness of the significant role ...

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  Residual Solvent Analysis

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Organic volatile impurities (OVIs), generally represent the chemical compounds in products, and are mainly produced by incomplete removal of the residual solvent during the manufacturing of active pharmaceutical ingredients (APIs), excipients and dru...

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  Stability Studies

  Drug Development Shirley (New York) April 1, 2019 Check with publisher

  Stability studies have critical effect on the pharmaceutical development since it provides the essential data that illustrates how the environmental factors such as temperature, humidity and photostability influence the quality of drug products. When...

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  Rho-kinase (Human) Assay Kit

  Drug Development Shirley (New York) March 29, 2019 10.00 Dollar US$

  Rho-kinase (Human) Assay Kit is a single-site, non-quantitative immunoassay for Rho-kinase activity. Plates are pre-coated with a substrate corresponding to recombinant the C terminus of MBS (Myosin-Binding Subunit of myosin phosphatase), which conta...

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  Rac Activation Kit

  Drug Development Shirley (New York) March 29, 2019 10.00 Dollar US$

  Rac Activation Kit provides a rapid, cost-effective and reliable tool for detection and semi-quantitative analysis of the cellular activation state of Rac1 and Rac2 G-proteins. If combined with immunological detection of Cdc42, the kit can also detec...

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  PTP1B Inhibitor Screening Assay Kit

  Drug Development Shirley (New York) March 29, 2019 10.00 Dollar US$

  PTP1B Inhibitor Screening Assay Kit is a colorimetric, non-radioactive assay designed to measure the phosphatase activity of purified PTP1B. This 96-well assay is useful for screening inhibitors and modulators of PTP1B activity. The kit includes Huma...