Immunology

Listings

• 

  JMJD5 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009...

• 

  JAKMIP2 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results i...

• 

  IRGM (AB2) Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal exp...

• 

  IRF7 (AB2) Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta ch...

• 

  IRF3 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates ...

• 

  IRE1p (AB3) Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expre...

• 

  IRAK4 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and re...

• 

  IPR1 (AB2) Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can...

• 

  Integrin alpha 4 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chain...

• 

  IL-17RE Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the im...

• 

  IL-27 (AB2) Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B),...

• 

  IL-1F10 Peptide

  Immunology Shirley (New York) September 3, 2021 Check with publisher

  The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin ...