Cav1.2

  • 1.00 Dollar US$
  • Published date: September 27, 2024
    • Shirley, New York, United States
Cav1.2
Cav1.2

Cav1.2 plays an important role in the contraction of the heart. It is particularly important and well known for its expression in the heart where it mediates L-type currents, which causes calcium-induced calcium release from the ER Stores via ryanodine receptors. The block of calcium current can lead to AV block and negative inotropy. Cav1.2 depolarizes at -30mV and helps define the shape of the action potential in cardiac and smooth muscle.

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Hannah Cole
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