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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Magic™ Humanized PD-1 Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1 Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Management of cancer is a big problem, not only because the difficulties in developing new drugs but also because tumor cells usually acquire resistance to anti-cancer drugs to avoid immune destruction (immune escape). One of the most important mecha...

  • Magic™ Humanized LAG3 Immune Checkpoint Knock-In Mice

    Magic™ Humanized LAG3 Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Recent achievements in cancer immunotherapy especially immune checkpoint modulators are reshaping the way of conventional cancer treatment. Nowadays, the rapid development of immune checkpoint targeting drugs has become one of the hotspots that are a...

  • MtoZ Biolabs provides ADCs  analysis

    MtoZ Biolabs provides ADCs analysis

    Bioinformatics - Data Analysis Boston (Massachusetts) September 29, 2019 Check with publisher

    As continuous development of Antibody-drug conjugates (ADCs) and the improving needs for precise determination of drug structure, drug characterization technology has also been constantly updated. When the traditional mass spectrometer technology can...

  • Meloxicam [KLH]

    Meloxicam [KLH]

    Molecular Biology Shirley (New York) August 26, 2019 10.00 Dollar US$

    Non steroidal anti inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic, antipyretic and, in higher doses, anti inflammatory effects - they reduce pain, fever and inflammation. Creative Diagnostics is an evolving biote...

  • Peptide Analysis Services

    Peptide Analysis Services

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptides are a general term for biologically active substances involved in various cellular functions in living organisms, and are often used in functional analysis, antibody research, and especially in drug development. In order to apply peptides be...

  • Peptide Drug Discovery

    Peptide Drug Discovery

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide drug refers to a peptide having a specific therapeutic effect extracted by chemical synthesis, genetic recombination or animal or plant, and is a specific application of the peptide in the field of medicine. The biological activity of the pep...

  • Stapled Peptide Synthesis

    Stapled Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra...

  • Peptoid Synthesis

    Peptoid Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptoids, or poly-N-substituted glycines, are a class of peptidomimetics whose side chains are appended to the nitrogen atom of the peptide backbone, rather than to the α-carbons (as they are in amino acids). Notably, peptoids lack the amide hydrogen...

  • Cyclic Peptide synthesis

    Cyclic Peptide synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Cyclic Peptides

    Cyclic Peptides

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Peptide PEGylation

    Peptide PEGylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    It has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. The driving force for this interest is the ability of these compounds to eliminate toxic or overproduced compounds in the body and to mimic endogenous hormones, ...

  • Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents

    Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents

    Molecular Biology Kyiv (Kyivska) July 5, 2019 Check with publisher

    Trypanosomatid and plasmodium parasites are producing a great deal of chronic diseases and affecting hundreds of millions people mainly in developing countries. However, in the last years, such diseases are dramatically disseminating worldwide, due t...