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Characterization and functional analysis of a novel cancer-associated gene
PhD Studentships Liverpool May 15, 2016 Check with publisherGenes involved in common biological processes and diseases tend to be co-expressed. Therefore, genes co-expressed with known disease-associated genes will help identify new candidates for further studies. Our lab has recently developed a co-expressio...
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Expertise in genomics and transcriptomics
Data Analysis - Analytics August 24, 2015 Check with publisherI lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...
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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
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Oncolytic Virus
Bioinformatics - Data Analysis Shirley (New York) August 26, 2024 1.00 Dollar US$Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequently spread with a tumor while not causing damage to normal cells. Besides the direct oncolytic activity, OVs are also effective in st...
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Modified Enzyme
Bioinformatics - Data Analysis Shirley (New York) August 26, 2024 1.00 Dollar US$Creative Biogene’s modification enzymes, including DNA and RNA polymerases, phosphatases, kinases, ligases, nucleases, methyltransferases, DNA repair proteins, recombinases etc, are used for a variety of molecular biology applications such as PCR amp...
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cDNA Synthesis Kits
Bioinformatics - Data Analysis Shirley (New York) August 26, 2024 1.00 Dollar US$cDNA synthesis (complementary DNA synthesis) is the process of transforming RNA molecules existing in samples into DNA in complementary sequences. cDNA synthesis enables researchers to convert RNA into stable cDNA, which can be used for downstream ap...
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Human TRPV3 Stable Cell Line
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$The TRPV3 channel belongs to the transient receptor potential channel (TRP) super-family that consists of 7 subfamilies. The channels exist as tetramers where each subunit consists of 6 putative trans-membrane domains. In this respect they have a sim...
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Cav1.2
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$Cav1.2 plays an important role in the contraction of the heart. It is particularly important and well known for its expression in the heart where it mediates L-type currents, which causes calcium-induced calcium release from the ER Stores via ryanodi...
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Human SCN8A Stable Cell Line
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$The human SCN8A gene encodes the pore-forming subunit of Nav1.6, a voltage-gated sodium channel expressed in central and peripheral nervous systems. Mutations in the mouse ortholog cause ataxia and other movement disorders. Nav1.6 channels are therap...
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Fluorescein RNA Labeling Kit
Molecular Biology Shirley (New York) September 27, 2024 1.00 Dollar US$Fluorescein RNA Labeling Kit (T7) is designed to generate randomly fluorescein-modified RNA probes by in vitro transcription. Such probes are suited for in situ hybridization and Northern blot hybridization experiments. https://integraterna.creative-...
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All-in-One T7 ARCA mRNA Synthesis Kit
Molecular Biology Shirley (New York) September 27, 2024 1.00 Dollar US$All-in-One T7 ARCA mRNA Synthesis Kit is designed for quick production of ARCA capped and poly(A) tailed mRNA in vitro. RNA synthesized using this kit can be used in a wide range of applications, such as in vitro translation, antisense RNA and RNAi e...
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5-Methoxy-UTP
Molecular Biology Shirley (New York) September 27, 2024 1.00 Dollar US$5-Methoxy-UTP is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. The Incorporation of 5-Methoxy-UTP can reduce the mRNA immunogenicity. https://integraterna.creative-biogene.com/5-methoxy-utp-item-rsnk-019-471383....
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COPD Models
Immunology Shirley (New York) October 30, 2024 1.00 Dollar US$Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. It is characterized by chronic airway inflammation, excessive mucus secretion, airway remodeling, and emphysema, leading to decreased lung function ...
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Bacterial Probes
Immunology Shirley (New York) October 30, 2024 1.00 Dollar US$FISH Probes were designed by sequencing the 16S rRNA for each bacterium, identifying hypervariable regions, and chemically synthesizing species-specific probes. These probes were specific when tested against a panel of nucleic acids from closely rela...
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PDX-based Drug Screening
Immunology New York (New York) October 30, 2024 1.00 Dollar US$To better preserve the genomic integrity and tumor heterogeneity observed in patients, patient-derived xenograft (PDX) models were generated using freshly resected patient tumors immediately transplanted into immunocompromised murine hosts without an...
