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Characterization and functional analysis of a novel cancer-associated gene
PhD Studentships Liverpool May 15, 2016 Check with publisherGenes involved in common biological processes and diseases tend to be co-expressed. Therefore, genes co-expressed with known disease-associated genes will help identify new candidates for further studies. Our lab has recently developed a co-expressio...
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Expertise in genomics and transcriptomics
Data Analysis - Analytics August 24, 2015 Check with publisherI lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...
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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
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Anti-MBP (ENPVVHFFKNIVTPR) TCR-Like Antibody (MK16), HLA-DR2b-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-p53 (RMPEAAPPV) TCR-Like Antibody (T1-84C), HLA-A*0201-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-CD4 (CE9γ4E) h(Fab-γδ TCR) Antibody T Cell Receptor, pCDTCR1
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherThe AbTCR fuses an antigen-binding domain from anti-CD4 (CE9γ4E) antibody with the C- terminal signaling domain of a γδTCR. More specifically, the antigen-binding domain of our AbTCR is an antibody Fab fragment, and the cellular-activation domain of ...
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Anti-FAP (3F2) h(Fab-γδ TCR) Antibody T Cell Receptor, pCDTCR1
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherThe AbTCR fuses an antigen-binding domain from anti-FAP (3F2) antibody with the C- terminal signaling domain of a γδTCR. More specifically, the antigen-binding domain of our AbTCR is an antibody Fab fragment, and the cellular-activation domain of con...
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Anti-p53 (RMPEAAPPV) TCR-Like Antibody (T1-29D), HLA-A*0201-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-HLA-A2 (SDWRFLRGYHQYA) TCR-Like Antibody (UL-5A1), HLA-DR1-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-p53 (RMPEAAPPV) TCR-Like Antibody (T1-116C), HLA-A*0201-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-CD4 (CE9.1) h(Fab-γδ TCR) Antibody T Cell Receptor, pCDTCR1
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherThe AbTCR fuses an antigen-binding domain from anti-CD4 (CE9.1) antibody with the C- terminal signaling domain of a γδTCR. More specifically, the antigen-binding domain of our AbTCR is an antibody Fab fragment, and the cellular-activation domain of c...
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Anti-TARP (FLRNFSLML) TCR-Like Antibody (Fab-D2), HLA-A*0201-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-MCC (IAYLKQATK) TCR-Like Antibody (G35), I-Ek-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-Melan-A/MART-1 (EAAGIGILTV) TCR-Like Antibody (CLA12), HLA-A*0201-Restricted
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherTCR-like monoclonal antibodies (TCR-like mAbs), which recognise a specific peptide in association with an MHC molecule (human leukocyte antigen, HLA in humans), permit the targeting of such inaccessible nuclear or cytoplasmic tumor- or virus-associat...
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Anti-DR5 (Apomab) h(Fab-γδ TCR) Antibody T Cell Receptor, pCDTCR1
Cell Biology & Microbiology (United States ) April 10, 2021 Check with publisherThe AbTCR fuses an antigen-binding domain from anti-DR5 (Apomab) antibody with the C- terminal signaling domain of a γδTCR. More specifically, the antigen-binding domain of our AbTCR is an antibody Fab fragment, and the cellular-activation domain of ...
