Premium listings
  • Characterization and functional analysis of a novel cancer-associated gene

    Characterization and functional analysis of a novel cancer-associated gene

    PhD Studentships Liverpool May 15, 2016 Check with publisher

    Genes involved in common biological processes and diseases tend to be co-expressed. Therefore, genes co-expressed with known disease-associated genes will help identify new candidates for further studies. Our lab has recently developed a co-expressio...

  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

  • Expertise in genomics and transcriptomics

    Expertise in genomics and transcriptomics

    Data Analysis - Analytics August 24, 2015 Check with publisher

    I lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...

Listings
  • Indomethacin-Induced Rodent Inflammation in Small Intestine

    Indomethacin-Induced Rodent Inflammation in Small Intestine

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Crohn's disease (CD) is a chronic condition observed in human and animal species affecting the gastrointestinal tract. It is one of the forms of Inflammatory Bowel Disease (IBD) complex, while the other being Ulcerative Colitis (UC). Animal models fo...

  • Magic™ Humanized PD-L1/TIM-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-L1/TIM-3 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Immune checkpoint inhibitors have been regarded as a powerful new class of anticancer therapy. They have changed the clinical treatment method for a series of tumor types, including melanoma, non-small cell lung cancer, breast cancer, etc. Nowadays, ...

  • Magic™ Humanized PD-1/BTLA Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/BTLA Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Immune checkpoint inhibitors, which target coinhibitory T cell molecules to promote anticancer immune responses, are now regarded as a novel cancer therapy of enormous potential. Nowadays, defining new targets and combination of immune checkpoint inh...

  • Magic™ Humanized PD-1/TIM-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/TIM-3 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Co-inhibitory or immune checkpoint receptors have a key function in the maintenance of immune homeostasis: their expression on effector T cells allows the proper contraction of effector T cell responses and their expression on regulatory T (Treg) cel...

  • Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    The therapy of using monoclonal antibodies against inhibitory receptors on immune cells, termed immune-checkpoint blockade, for the treatment of human cancer has gained a great deal of attention among clinicians, scientists, and patients. Checkpoint ...

  • Ovariectomy (OVX)-Induced Osteoporosis in Rats

    Ovariectomy (OVX)-Induced Osteoporosis in Rats

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures. The incidence of osteoporosis increases with age and occurs most frequently ...

  • Transposon-Mediated Genome Manipulation

    Transposon-Mediated Genome Manipulation

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Transposons-based genetic strategies have been established in vertebrate species over the last decade. The major advantage of these strategies is that they facilitate analysis of gene function in an easy, controlled, and scalable manner, thereby avoi...

  • Reference Standard Preparation and Characterization

    Reference Standard Preparation and Characterization

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    A reference standard material is defined as highly purified compound that is well characterized by FDA (US Food and Drug Administration), and highly characterized specimens of drug substances, excipients, reportable impurities, degradation products, ...

  • Magic™ Humanized CD40 Immune Checkpoint Knock-In Mice

    Magic™ Humanized CD40 Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    The TNFR (Tumor Necrosis Factor Receptor) superfamily members are considered as appealing candidates for the development of targeted immunotherapies. Recently, a great attention has been focused upon a member of TNFR superfamily, CD40 (also known as ...

  • Magic™ Humanized TIM-3 Immune Checkpoint Knock-In Mice

    Magic™ Humanized TIM-3 Immune Checkpoint Knock-In Mice

    Molecular Biology Shirley (New York) October 30, 2019 Check with publisher

    T-cell inhibitory receptor TIM-3 (T-cell immunoglobulin and mucin domain 3) is expressed on Th1, Th17, CD8+ T cells and it is a T cell inhibitory receptor. TIM family is a kind of membrane protein, which contains three parts: a variable immunoglobuli...

  • Magic™ Humanized CTLA-4 Immune Checkpoint Knock-In Mice

    Magic™ Humanized CTLA-4 Immune Checkpoint Knock-In Mice

    Molecular Biology Shirley (New York) October 30, 2019 Check with publisher

    As a leading provider in the field of antibody discovery, development and manufacture, Creative Biolabs has successfully launched, commercialized and optimized an exclusive Magic™ therapeutic antibody discovery platform. Of note, as increasing attent...

  • Anti-Denv-1 Polyprotein Antibody

    Anti-Denv-1 Polyprotein Antibody

    Biological Sciences Shirley (New York) October 29, 2019 Check with publisher

    This product is a mouse antibody that specifically recognizes Polyprotein from Denv-1. The antibody 15F3-1 is an epitope-specific antibody that can be used in WB, ELISA, Inhib and other immunological assays. Dengue virus (DENV) in one of four serotyp...