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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Peptide Analysis Services

    Peptide Analysis Services

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptides are a general term for biologically active substances involved in various cellular functions in living organisms, and are often used in functional analysis, antibody research, and especially in drug development. In order to apply peptides be...

  • Peptide Drug Discovery

    Peptide Drug Discovery

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide drug refers to a peptide having a specific therapeutic effect extracted by chemical synthesis, genetic recombination or animal or plant, and is a specific application of the peptide in the field of medicine. The biological activity of the pep...

  • Stapled Peptide Synthesis

    Stapled Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra...

  • Peptoid Synthesis

    Peptoid Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptoids, or poly-N-substituted glycines, are a class of peptidomimetics whose side chains are appended to the nitrogen atom of the peptide backbone, rather than to the α-carbons (as they are in amino acids). Notably, peptoids lack the amide hydrogen...

  • Cyclic Peptide synthesis

    Cyclic Peptide synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Cyclic Peptides

    Cyclic Peptides

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Peptide PEGylation

    Peptide PEGylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    It has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. The driving force for this interest is the ability of these compounds to eliminate toxic or overproduced compounds in the body and to mimic endogenous hormones, ...

  • Reaction Condition Optimization

    Reaction Condition Optimization

    Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher

    As new drugs continue to be marketed, strategies to improve drug development and manufacturing processes become critical. In the development of pharmaceutical and chemical products, it is becoming more and more important to improve the yield, reduce ...

  • Amination

    Amination

    Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher

    Amination is the reaction process of introducing amine groups (-NH2) into organic molecules to form amines. Amines as a very potent drug functional group exist in most drug structures. For example, cyclized amines are considered to be the pharmacopho...

  • Peptide Synthesis

    Peptide Synthesis

    Clinical/Medical Sciences Shirley (New York) February 11, 2019 Check with publisher

    Peptides are central compounds in the pharmaceutical industry, providing both final medications and lead compounds for the preparation of peptidomimetic or non-peptidic pharmaceuticals. Therapeutic peptides are recognised as being extremely specific ...

  • Carbohydrate Synthesis

    Carbohydrate Synthesis

    Clinical/Medical Sciences Shirley (New York) February 11, 2019 Check with publisher

    Carbohydrates, an important class of natural products, play a wide range of key roles in complex biological processes involving specific events in vital cellular recognition processes, carbohydrate-protein interactions, and targeting of hormones, ant...

  • PEGylation

    PEGylation

    Clinical/Medical Sciences Shirley (New York) February 11, 2019 Check with publisher

    Polyethylene glycol (PEG) modification, also known as molecular PEGylation, is a promising technology developed in the late 1970s and widely used to improve delivery in pharmaceutical applications. Most chemical drugs and proteins, peptides and other...